![]() Transappendageal or follicular absorption -Ĭompounds can enter skin through the openings that already exist in your skin as conduits between the lower and upper layers. Only very tiny molecules can absorb into skin this way. This layer of skin is 15 to 20 layers thick. The second route of absorption is through the dense, functionally dead cells of the outermost layer of skin, the Stratum Corneum. The fact that it is oil based means that oils have a good chance of absorbing this way, while water based ingredients will be repelled since oil and water do not mix well. The intercellular lipid material is made up of ceramides, cholesterol, cholesterol esters, and fatty acids. Ingredients can absorb through the “glue” between cells of the stratum corneum. There are three ways that chemicals enter into skin. Wondering if all ingredients eventually absorb? Since chemicals come in different sizes and have different absorption rates, not all of them are able to absorb into the body. Ingredients will do their best work to hydrate and condition if they can get into the skin, but not leave the skin itself. Absorption is when a chemical enters the bloodstream. When a chemical penetrates the skin it makes its way past the stratum corneum (the outer layer of skin) and into skin’s deeper layers. While they sound very similar, and are often used interchangeably in the cosmetics world, there is a big distinction. The Difference Between Skin Absorption and Penetrationīefore we get too deep into the subject of skin absorption rate, it’s essential to know the difference between penetration and absorption. ![]() And you don’t need a degree in chemistry to figure it out. Learning a bit more about the truths of dermal absorption will leave you better able to choose what’s right for your skin and body. There are also variations in what the body holds onto, chemical wise, and how chemicals react in the body once they are absorbed. For starters, there’s a big difference between skin penetration and absorption, and not all ingredients absorb into the skin in the same amount. Unfortunately (or maybe, fortunately) the facts on chemical absorption through skin aren’t that simple. Yet many companies and websites have posted that finding repeatedly as if it applies to everything. Solvents have an exceptional ability to disrupt the skin barrier, so the skin absorption rate for a solvent will be higher than most other compounds. While it is important to take chemical absorption through skin into account – it is, after all, the basis for many people switching to natural cosmetics – you can’t believe everything you read.įor starters, that 60% figure that is so commonly thrown around? It’s really misleading.Ī study that showed an average of 64% skin absorption rate was using solvents like toluene, xylene, and methylene chloride as the compounds tested for skin absorption. The subject of skin absorption and cosmetics is full of inaccuracies.
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